p53 (a.a. 16-25) is a transcription factor that acts as a tumor suppressor which cause growth arrest or apoptosis depending on different circumstances or cell type. p53 also play an important role in cell cycle regulation as a trans-activator. The most common alteration in human cancer is disruption of the p53 signalling pathway through various mechanisms.
应用类型
ELISA (ELISA), Immunoprecipitation (IP), Western blot (WB)
