B-synuclein (amino acids 1-134), an acidic neuronal protein of 134 amino acids, is extremely heat-resistant. B-synucelin also has a chaperone-like activity. Recently, B-synuclein has been suggested to inhibit a-synuclein aggregation. B and a-synuclein are abundantly expressed in the brain and putatively inhibit phospholipase D2 selectively. The encoded protein, which may play a role in neuronal plasticity, is abundant in neurofibrillary lesions of patients with Alzheimer disease.
应用类型
ELISA, Western blot
免疫原
Recombinant human B-Synuclein amino acids 1-134 purified from E. coli.