Caseine Kinase 1 alpha belongs is a member of the protein kinase superfamily， CK1 Ser/Thr protein kinase family， Casein kinase I subfamily. The CK1 isoforms - alpha， beta， gamma， delta， epsilon and their splice variants are involved in diverse cellular processes including membrane trafficking， circadian rhythm， cell cycle progression， chromosome segregation， apoptosis and cellular differentiation. Possibly CSNK1A1 can phosphorylate a large number of proteins and is involved in Wnt signaling where it phosphorylates CTNNB1 on Ser45. CSNK1A1 also interacts with the Axin complex.
应用类型
ELISA， Western blot
免疫原
Anti-human CSNK1A1 mAb， is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CSNK1A1 amino acids 1-337 purified from E. coli.
