PPM1B belongs to the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. The PPM1B phosphatase can dephosphorylate cyclin-dependent kinases （CDKs）， and thus may be involved in cell cycle control. Overexpression of the PPM1B phosphatase is reported to cause cell-growth arrest or cell death.
应用类型
ELISA， Western blot
免疫原
Anti-human PPM1B mAb， is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PPM1B amino acids 1-192 purified from E. coli.
