PPP1CA is one of the 3 catalytic subunits of protein phosphatase 1 （PP1）. PP1 is a serine/threonine specific protein phosphatase which is involved in the regulation of a variety of cellular processes， such as cell division， glycogen metabolism， muscle contractility， protein synthesis， and HIV-1 viral transcription. Increased PP1 activity is detected in the end stage of heart failure. Studies in both human and mice suggest that PP1 is a significant regulator of cardiac function. Mouse studies also propose that PP1 functions as a suppressor of learning and memory.
应用类型
ELISA， Western blot
免疫原
Anti-human PPP1CA mAb， is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PPP1CA amino acids 30-299 purified from E. coli.
