GSK3B is a serine-threonine kinase that belongs to the glycogen synthase kinase subfamily. GSK3B is involved in energy metabolism， neuronal cell development， and body pattern formation. Polymorphisms in the GSK3B gene have been implicated in modifying risk of Parkinson disease， and studies in mice show that overexpression of the GSK3B gene may be significant to the pathogenesis of Alzheimer disease.
应用类型
ELISA， Western blot
免疫原
Anti-human GSK3B mAb， is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human GSK3B amino acids 341-420 purified from E. coli.
