Cyclophilin B （also known as PPIB， peptidylpropyl isomerase B） is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes， and may regulate cyclosporine A-mediated immunosuppression.
应用类型
ELISA， Western blot
免疫原
Anti-human Cyclophilin-B mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human Cyclophilin-B amino acids 26-216 purified from E. coli.
