RAB5A is a member of RAS oncogene family. The small GTPase， RAB5A is a crucial regulatory component of the endocytic pathway. Activation of RAB5A is mediated by GDP-GTP exchange factors （GEFs） that generate the Rab5-GTP complex）. RAB5A is required for the fusion of plasma membranes and early endosomes.
应用类型
ELISA， Western blot
免疫原
Anti-human RAB5A mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human RAB5A amino acids 1-215 purified from E. coli.
