CRP is an acute phase protein that correlates with inflammatory disease and is synthesized by hepatocytes during the acute phase response by certain cytokines （IL-1 and TNF Alpha and Beta）. CRP levels increase dramatically （up to 1，000 fold） and serve as a useful marker of inflammation in such conditions as bacterial infection， rheumatoid arthritis， viral infections， transplantation rejection， meningitis， myocardial infarction， septicemia， osteomyelitis and others. CRP is also highly correlated to Serum Amyloid A levels.
应用类型
ELISA， Western blot
免疫原
Anti-human CRP mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CRP amino acids 19-224 purified from E. coli.
