GroEL， HSP60 is a chaperonin located in the mitochondria which is responsible for the transportation & refolding of proteins from the cytoplasm directly into the mitochondrial matrix. GroEL is regulated by the HSP10 cochaperonin， which is a single heptameric protein ring having a molecular mass of 10 kDa which form a unique complex with HSP60. HSP10， GroES coordinates the ATPase activity of the HSP60 subunits in order to allow the release of bound polypeptide in a manner that is productive for its correct folding.
应用类型
ELISA， Western blot and immunohistochemistry
免疫原
Anti-human GroEL mAb， is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human GroEL amino acids 1-573 purified from E. coli.
