HSP27 （also known as the Estrogen-Regulated 24K protein， and hsp 28） is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures， toxic metals， drugs and oxidants. Also， Hsp27 is phosphorylated in vivo on three phosphorylation sites （Ser15， Ser78 and Ser82） by protein kinases including MAPKAP kinase 2 and the stress-activated protein kinase SAPK2 （p38）.
应用类型
ELISA， Western blot and immunohistochemistry
免疫原
Anti-human HSP27 mAb， is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HSP27 amino acids 1-205 purified from E. coli.
