MHC Class I is a membrane spanning molecule consisting of 2 proteins. MHC Class I is just about 350 amino acids in length， with roughly 75 amino acids at the carboxylic end comprising the transmembrane and cytoplasmic portions. The remaining 270 amino acids， are divided into three globular domains labeled Alpha-1， Alpha-2 and Alpha-3 prime， with Alpha-1 being closest to the amino terminus and Alpha-3 closest to the membrane. The second portion of the molecule is a small globular protein called Beta-2 Microglobulin It links primarily with the Alpha-3 prime domain and is essential for MHC stability.
应用类型
Cytotoxic and staining antibody.
免疫原
Purified mouse LN cells （C57Bl/6 anti-BALB/c）.
来源宿主
小鼠
反应性
Recognizes most mouse H-2K haplotypes （k，p，q，r，s）。 Does NOT react with H-2kd
