SARS Coronavirus is an enveloped virus containing three outer structural proteins， namely the membrane （M）， envelope （E）， and spike （S） proteins. Spike （S）-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly， S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.
应用类型
western blot
免疫原
The antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 1124-1140 of the putative SARS Spike glycoprotein （Genbank accession no. NP_828851）.
