HCV is a small 50nm, enveloped, single-stranded, positive sense RNA virus in the family Flaviviridae. nHCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host’s immune response. Hepatitis C virus is classified into six genotypes (1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
应用类型
【HCV NS3】小鼠抗丙型肝炎病毒NS3抗体Mouse Anti Hepatitis C Virus NS3该产品的应用类型查阅产品说明书。