CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor， and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell （APC） in the context of class I MHC molecules. The functional CD8 is either a homodimer composed of two alpha chains， or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
应用类型
Blocking and staining antibody. For staining， use 10μl/1，000，000 cells. Titer for blocking T cell activation should be determined by the investigator.
