The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells CD-80 is involved in the costimulatory signal essential for t- lymphocyte activation. t-cell proliferation and cytokine production is induced by the binding of cd28 or ctla-4 to this receptor.
应用类型
Blocking and staining antibody. For staining, use 10μl/1,000,000 cells. Titer for blocking T cell activation should be determined by the investigator.