Mediator of ErbB2-driven cell motility 1 （MEMO1） is a member of the UPF0103 family. MEMO1 regulates cell migration by transmitting extracellular chemotactic signals to the microtubule cytoskeleton. Furthermore， MEMO1 controls the localization of APC and CLASP2 to the cell membrane， using the regulation of GSK3B activity. MEMO1 is essential for breast carcinoma cell migration， suggesting a key role in tumorigenesis. MEMO1 is also a mediator of ERBB2 signaling.
应用类型
【MEMO1】小鼠抗人细胞运动调节蛋白1Mouse Anti Human Mediator of Cell Motility 1该产品的应用类型查阅产品说明书。
免疫原
Anti-human MEMO1 mAb， is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human MEMO1 amino acids 1-297 purified from E. coli.
