Glutamate-cysteine ligase (GCLM) is the first rate limiting enzyme of glutathione synthesis. The GCLM enzyme is comprised of 2 subunits, a heavy catalytic subunit and a light regulatory subunit. GCLM deficiency is associated with some forms of hemolytic anemia.
应用类型
【GCLM】小鼠抗人谷氨酸半胱氨酸连接酶修饰亚基抗体Mouse Anti Human Glutamate-Cysteine Ligase, Modifier Subunit该产品的应用类型查阅产品说明书。
免疫原
Anti-human GCLM mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human GCLM amino acids 1-274 purified from E. coli.