LSM2 is a member of the snRNP Sm proteins family. Sm-like proteins are branded in several organisms based on sequence homology with the Sm protein family. Sm-like proteins hold the Sm sequence motif that is made up of 2 regions separated by a linker of variable length which folds as a loop. The Sm-like proteins are believed to create a steady heteromer present in tri-snRNP particles， which are vital for pre-mRNA splicing. LSM2 binds specifically to the 3’-terminal U-tract of U6 snRNA nad takes part in pre-mRNA splicing.
应用类型
ELISA， Western blot
免疫原
Anti-human LSM2 mAb， is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human LSM2 amino acids 1-95 purified from E. coli.
