肿瘤坏死因子(Tumor Necrosis Factor,TNF)可分为TNF a和TNFB两种,前者来自单核巨噬细胞,后者由活化T细胞产生,是具有重要生物活性的细胞因子.存在于细胞上的TNF 受体主要有两种:TNFRⅠ和TNFRⅡ,血清中存在的是可溶性的TNFR(s TNFRⅠ, s TNFRⅡ),它们的相互作用不仅对多种肿瘤细胞有细胞毒作用,还与炎症和发热反应、关节炎、败血症及多发性硬化等疾病有密切关系
应用类型
ELISA, Western blot and Immunofluorescence
免疫原
Anti-human LTA mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human LTA amino acids 35-205 purified from E. coli.