Pyruvate kinase is a key enzyme in the glycolytic pathway. The M2 isoenzyme of pyruvate kinase is specifically expressed at high levels in tumor cells， and can be measured in plasma of patients with advanced breast cancer. The marker is useful for measuring disease activity， sensitivity to chemotherapy and recurrence.
应用类型
ELISA， Western blot and Immunofluorescence
免疫原
Anti-human PKM2 mAb， is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PKM2 amino acids 1-531 purified from E. coli.
