DERP1 is a thiol protease， with a preference for substrates with a large hydrophobic side chain in the P2 position， or with basic residues. DERP1 is a C1 peptidase family member. DERP1 has extensive endopeptidase specificity. DERP1 is N-glycosylated. N-glycanase treatment does not completely remove carbohydrates， suggesting that the protein contains additional glycosylation sites. DERP1 causes an allergic reaction in humans. Common symptoms of mite allergy are bronchial asthma， allergic rhinitis and conjunctivitis. DERP1 binds to IgE in 80% of patients with house dust allergy.
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来源宿主
大肠杆菌中重组表达
溶解建议
10mM Tris-HCl， pH 6.5， 100mM Sodium Phosphate and 8M urea.
保存建议
Five years frozen. One month in solution at room temperature.
