Tropicamide is a muscarinic receptor antagonist, which shows a 3 fold selectivity for m4. Its effect has a pIC50 of ~7.5 for porcine intravesical ureter contraction.
产品描述
A Potent Muscarinic Receptor Antagonist
产品形式
Muscarinic acetyl choline receptors (mAChR) regulate a number of important basic physiologic functions including heart rate, motor and sensory control and more complex behaviors including arousal, memory, and learning. Loss of muscarinic receptor number or function has been implicated in the etiology of several neurological disorders including Alzheimer's dementia, Down's syndrome and Parkinson's disease.