RY796 is a synthetic blocker of the KV2.1 and KV2.2 channels. It has an effective concentration of 0.1-10 µM and an IC50 of 0.09 µM and 0.25 µM for the KV2.1 and KV2.2 channels respectively. RY796 has greater selectivity for KV2 channels over other KV channels out of 1894 compounds in a study conducted by Herrington, J. et al. In addition, RY796 does not affect other ion channels such as sodium and calcium.