Pancuronium bromide is a competitive neuromuscular blocking agent and a skeletal muscle relaxant. It is a bulky molecule of Bovet's pachycurare type and therefore has a nondepolarising mechanism of action.
产品描述
A Potent nAChR Antagonist
产品形式
nAChRs are members of the Cys-Loop ligand-gated ion channel superfamily, located both in the peripheral and central nervous systems (PNS and CNS, respectively). They mediate rapid synaptic transmission by increasing the conductance of the postsynaptic cell membrane in response to nerve-released acetylcholine (ACh) and are validated therapeutic targets for various CNS pathologies.
