MT-7 is a 65 amino acid peptide toxin isolated from the Dendroaspis angusticeps (Eastern green mamba). It was first found to inhibit M1 muscarinic receptors stably transfected in CHO cells at very low concentrations (1-30 nM)6 and acts as a non-competitive antagonist by binding to an allosteric site.
产品描述
An Antagonist of M1 Muscarinic Receptor
产品形式
The action of the neurotransmitter acetylcholine (Ach) is mediated through two types of receptors, the ionotropic nicotinic receptors and the metabotropic muscarinic receptors. The muscarinic receptors belong to the superfamily of G-protein coupled receptors. Five subtypes of muscarinic receptors have been cloned: m1-m5.
保存建议
艾美捷为您提供的Alonmone Labs原装进口的MT-7 (5 X 20 µg)产品可室温运输,建议您在收到产品后将其置于合适的温度下保存。