- 中文名称
WRW4（5毫克）
- 英文名字
- WRW4
- 供应商
- Alomone
- 产品货号
- ALO-GPW-110-5
- 产品报价
- ￥已停产
- 产品说明书
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- 购买方式
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- 产品新闻
- 背景资料
- WRW4 is a selective and potent antagonist of the Formylpeptide receptors (FPR2 and FPR3), which was identified by screening hexapeptide libraries that inhibit the binding of the FPR2 agonist WKYMVm to its specific receptor, in RBL-2H3 cells. In human umbilical vein endothelial cells, WRW4 (10 mM), inhibited CCL2 production, which was stimulated by serum amyloid A.
- 产品描述
- A Potent Antagonist of FPR2 and FPR3 G-Protein Coupled Receptors
- 产品形式
- Chemotactic factors from both Gram-positive and Gram-negative bacteria are short peptides with N-formyl methionine at the N-terminus (extensively reviewed in reference 1). These peptides are released from bacteria during infection and activate formyl peptide receptor (FPR), a member of G-protein coupled receptors (GPCRs). In human, the FPR family consists mainly of three receptors, FPR1, FPR2/ALX (formerly FPRL1), and FPR3 (formerly FPRL2) which all couple to the Gi subtype of G-proteins and ultimately lead to the activation of phospholipase C and intracellular Ca2+ increase.
- 保存建议
- 艾美捷为您提供的Alonmone Labs原装进口的WRW4 (5 mg)产品可室温运输，建议您在收到产品后将其置于合适的温度下保存。
- 其他
- Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证，以冻干粉形式提供，可确保产品生物活性和保质期。Alomone可提供多种包装规格，灵活方便。作为Alomone Labs在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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