FTX is a polyamine component of the venom of the American funnel web spider Agelenopsis aperta, and has been described as a selective antagonist of P-type voltage-dependent Ca2+ channels. However, it has been demonstrated that FTX has actions at other sites including NMDA and GABA receptors and also on T-type calcium channels.
产品描述
A Blocker of P-Type CaV Channels
产品形式
Polyamine amide spider toxins inhibit neuronal voltage-activated Ca2+ currents. A terminal arginine group is an important feature of these Ca2+ channel antagonists.