- 中文名称
钙西汀（70 ug）
- 英文名字
- Calciseptine
- 供应商
- Alomone
- 产品货号
- ALO-C-500-70
- 产品报价
- ￥已停产
- 产品说明书
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- 购买方式
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- 产品新闻
- 背景资料
- Calciseptine is a natural peptide isolated from the Dendroaspis p. polylepsis black mamba venom, by a modification to the procedure of Schweitz et al. and purified to homogenity. Calciseptine was shown to be a specific L-type Cav channel blocker. In contrast, it increases L-type currents in skeletal muscle.Calciseptine blocks spontaneous or K+-induced contraction of cardiac and smooth muscle cells. Using patch clamp, it was also shown to block specifically L-type Cav channel current in neuronal cells in culture. For these variety of effects, the IC50's were in the range of 15-500 nM. Using the outside-out configuration of patch clamp, it was shown to reduce single L-type channels open probability and availability as recorded from Guinea pig portal vein.
- 产品描述
- A Specific Blocker of L-type CaV Channels
- 产品形式
- Calciseptine is a natural peptide isolated from the Dendroaspis p. polylepsis black mamba venom, by a modification to the procedure of Schweitz et al. and purified to homogenity. Calciseptine was shown to be a specific L-type Cav channel blocker. In contrast, it increases L-type currents in skeletal muscle.Calciseptine blocks spontaneous or K+-induced contraction of cardiac and smooth muscle cells. Using patch clamp, it was also shown to block specifically L-type Cav channel current in neuronal cells in culture. For these variety of effects, the IC50's were in the range of 15-500 nM. Using the outside-out configuration of patch clamp, it was shown to reduce single L-type channels open probability and availability as recorded from Guinea pig portal vein.
- 保存建议
- 艾美捷为您提供的Alonmone Labs原装进口的Calciseptine (70 µg)产品可室温运输，建议您在收到产品后将其置于合适的温度下保存。
- 其他
- Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证，以冻干粉形式提供，可确保产品生物活性和保质期。Alomone可提供多种包装规格，灵活方便。作为Alomone Labs在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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