The toxin is selective for α7 receptors (IC50 value of 1.6 nM) and α3/β4 receptors (IC50 value of > 3 µM).nα-Bungarotoxin also binds to and blocks a subset of GABAA receptors (GABAARs) that contain the GABAAR β3 subunit. In particular, α-Bungarotoxin blocks GABAARs that contain interfaces between adjacent β3 subunits.
产品描述
A Potent Blocker of alpha7 and Muscle nAChR and GABA(A) Receptor Subtypes
产品形式
α-Bungarotoxin isoform A31 is a 74 amino acid peptidyl toxin isolated from the venom of the banded krait snake, Bungarus multicinctus.nα-Bungarotoxin blocks postsynaptic neuromuscular transmission via competitive inhibition of nicotinic ACh receptors (nAChRs) with an IC50 of 3.5 x 10 -10 M, thereby prevents the depolarizing action on postsynaptic membranes and blocks neuromuscular transmission.
保存建议
艾美捷为您提供的Alonmone Labs原装进口的Alpha-Bungarotoxin (5 x 1 mg)产品可室温运输,建议您在收到产品后将其置于合适的温度下保存。