Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues. In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain it acts as a neurotransmitter in both stimulatory and inhibitory manner.Somatostatin mediates its action via six high affinity G-protein coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4 and SSTR5) which are encoded by five genes.Expression of the different receptors is developmentally regulated in a time and tissue-specific manner.Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids and breast tumors. Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine malignancies and in in vivo imaging of tumors that are positive to somatostatin receptors.
应用类型
经验证，该抗体可应用于WB
免疫原
Somatostatin 受体 Type I (胞外)抗体的免疫原肽段为CSRGPGSGAADGMEE。此免疫原序列来源于26-40 位氨基酸残基，该序列来源于大鼠somatostatin 受体 type 1 (Accession编号为# P28646)。胞外，N端。
来源宿主
兔
反应性
反应性：大鼠
保存建议
艾美捷为您提供的Somatostatin 受体 Type I (胞外)抗体(50 ul)为室温运输，建议您收到产品后﹣20℃保存。
