Chapsyn 110 (also known as PSD-93 and DLG2) is a PDZ containing domain protein that is also a member of the membrane-associated guanylate kinase (MAGUK) family of multi-domain adaptor proteins.nPDZ domains are conserved protein domains of about 90 amino acids involved in protein–protein recognition, protein targeting and assembly of multi-protein complexes. The name PDZ derives from the first three proteins in which these domains were identified: PSD-95 (a 95 kDa protein involved in signaling at the post-synaptic density), DLG (the Drosophila melanogaster Discs Large protein) and ZO-1 (the zonula occludens 1 protein involved in maintenance of epithelial polarity)
应用类型
经验证,该抗体可应用于IC、IH、IP、 WB等实验。
免疫原
PSD-93抗体的免疫原肽段为含特定序列的GST融合蛋白: VEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSTPY。此免疫原序列来源于336-379 位氨基酸残基,该序列来源于大鼠chapsyn-110。 (Accession编号为Q63622)。 Between PDZ2和PDZ3 结构域s。