- 中文名称
KV10.1(EAG-1)抗体(50 ul)
- 英文名字
- Anti-KV10.1 (EAG-1)
- 供应商
- Alomone
- 产品货号
- ALO-APC-104-50
- 产品报价
- ¥已停产

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- KV10.1 is a member of the Ether-a-go-go family of voltage-activated K+ channels. To date, the family includes 8 members: the closely related KV10.2 (EAG-2) protein, the KV12 (elk) subfamily (elk1, elk2, elk3) and the KV11 (erg) proteins (erg1, erg2, erg3). As with the other KV superfamily members, KV10.1 shows the characteristic 6 transmembrane domains with intracelullar N and C termini.nThe KV10 subfamily current is characterized by outward rectification without inactivation and slow activation kinetics. Its expression is normally confined to the brain where its physiological function has not yet been clarified.nIntriguingly, the KV10.1 channel has been implicated in malignant tumor development. It has been shown that KV10.1 was inappropriately expressed in several cancer cell lines. Moreover, one study showed that KV10.1 by itself had oncogenic potential, as a cell line transfected with the channel, induced aggressive and faster tumor growth in vivo as compared to a cell line transfected with an unrelated KV channel.
- 应用类型
- 经验证,该抗体可应用于IC、IH、WB等实验应用,也可用于IFC、IP等实验。
- 免疫原
- KV10.1 (EAG-1)抗体的免疫原肽段为GDPAKRKGWARFKDAC。此免疫原序列来源于802-817 位氨基酸残基,该序列来源于大鼠KV10。1 (Accession编号为Q63472)。胞内, C端。
- 来源宿主
- 兔
- 反应性
- 反应性:人、 小鼠、 大鼠
- 保存建议
- 艾美捷为您提供的KV10.1 (EAG-1)抗体(50 ul)为室温运输,建议您收到产品后﹣20℃保存。
- 其他
- Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证,以冻干粉形式提供,可确保产品生物活性和保质期。Alomone可提供多种包装规格,灵活方便。作为Alomone Labs在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。

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