Kir2.1 is a member of the family of inward rectifying K+ channels. The family includes 15 members that are structurally and functionally different from the voltage-dependent K+ channels.The family’s topology consists of two transmembrane domains that flank a single and highly conserved pore region with intracellular N- and C-termini. As is the case for the voltage-dependent K+ channels the functional unit for the Kir channels is composed of four subunit that can assembly as either homo or heterotetramers.
应用类型
经验证，该抗体可应用于IC、IFC、IH、IP、WB等实验。
免疫原
Kir2.1抗体的免疫原肽段为(C)NGVPESTSTDTPPDIDLHN。此免疫原序列来源于392-410位氨基酸残基，该序列来源于人类Kir2。1 (Accession编号为P48049)。胞内, C-terminal part
