Glial cell-line derived neurotrophic factor (GDNF) is a neurotrophic factor originally identified for its ability to promote the survival of dopaminergic neurons in the midbrain.GDNF is part of the neurotrophic factor family known as GDNF-family ligand (GFL), which includes neurturin (NRTN), artemin (ARTN), and persephin (PSPN).The GFL ligands are structurally related to the transforming growth factor-b (TGF-b) protein superfamily and contain seven cysteine residues with the same relative spacing as other members of this family.Typical of neurotrophic factors, GDNF is produced in the form of a precursor, preproGDNF, which is then cleaved during secretion to become proGDNF, and later processed to the mature (homodimeric) GDNF form
应用类型
经验证，该抗体可应用于IC、IH、WB等实验应用等实验应用，也可用于 IP等实验。
免疫原
GDNF抗体的免疫原肽段为(C)DDNLVYHILRKHSAKR。此免疫原序列来源于192-207位氨基酸残基，该序列来源于人类GDNF (precursor) (Accession编号为P39905)。 C端 of the mature GDNF。
