The p75NTR receptor is a member of the TNF receptor superfamily. p75NTR, like all the superfamily members is a type I transmembrane protein with tandem cysteine-rich domains in the extracellular portion and a intracellular death domain. p75NTR binds its ligands as a homodimer but can also form heterodimers with other receptors such as TrkA, TrkB, TrkC, Nogo receptor and sortilin. The precise multimeric receptor complex formed between p75NTR and the other receptors will determine the ligand being recognized (see below) and the biological response to its binding
应用类型
经验证，该抗体可应用于IH、WB等实验应用，也可用于IC、IFC、IP等实验。
免疫原
Human p75NTR (intracellular)抗体的免疫原肽段为CKQNKQGANSRPVNQT 对应的氨基酸残基： 278-293人类氨基酸残基
