Brain derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors that includes nerve growth factor (NGF) neurotrophin-3 (NT-3) and neurotrophin-4/5 (NT-4/5).nAll neurotrophins are synthesized as preproneurotrophin precursors that are subsequently processed within the intracellular transport pathway to yield proneurotrophins that are further processed to generate the mature form. The mature form of BDNF is a non-covalent stable homodimer that can be secreted in both constitutive and regulated pathways.
应用类型
经验证，该抗体可应用于IH、WB等实验应用，也可用于IC、IFC、IP等实验。
免疫原
proBDNF抗体的免疫原肽段为(C)DEDQKVRPNEENNKDAD。此免疫原序列来源于72-88位氨基酸残基，该序列来源于人类BDNF (precursor) (Accession编号为P23560 )。 Pro-结构域 of the BDNF蛋白。
