- 中文名称
TRPML1抗体（50 ul）
- 英文名字
- Anti-TRPML1
- 供应商
- Alomone
- 产品货号
- ALO-ACC-081-50
- 产品报价
- ￥已停产
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868。
- 产品新闻
- 背景资料
- TRPMLs, also termed mucolipins, are members of the TRP channels. In mammals, three TRPMLs are known to date (TRPML1-3 or MCOLN1-3). They are all localized to endolysosomes, although when over expressed in heterologous systems, TRPML3 is found on the plasma membrane. These channels are Ca2+ permeable and display inward rectifying current properties. Like all members of this family, TRPMLs have six transmembrane domains and intracellular N- and C-termini (relatively short tails compared to other members). They are characterized by an exceptionally large extracellular (luminal) loop between transmembrane domains 1 and 2, and N-glycosylation sites are present in the first extracellular (luminal) loop.n In mammals, TRPML1 is expressed in a ubiquitous manner and shows highest expression in the brain, kidney, spleen, liver and heart. TRPML2 and TRPML3 are less widely expressed. Interestingly, in mouse, two splice variants exist for TRPML2. The shorter variant is more broadly expressed and is dominant over the longer variant in the thymus, spleen and kidney. TRPML3 is highly detected in the thymus, lung, kidney, spleen and eye, some epithelial cellsand brain.
- 应用类型
- 经验证，该抗体可应用于WB等实验应用，也可用于IC、IFC、IH、IP等实验。
- 免疫原
- TRPML1抗体的免疫原肽段为(C)GRRASETERLLTPN。此免疫原序列来源于 6-19 位氨基酸残基，该序列来源于小鼠 TRPLM1 (Accession编号为Q99J21)。胞内, N端 (细胞质)。
- 来源宿主
- 兔
- 反应性
- 反应性：人、 小鼠、 大鼠
- 保存建议
- 艾美捷为您提供的TRPML1抗体(50 ul)为室温运输，建议您收到产品后﹣20℃保存。
- 其他
- Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证，以冻干粉形式提供，可确保产品生物活性和保质期。Alomone可提供多种包装规格，灵活方便。作为Alomone Labs在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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