The α2C-Adrenoceptor subtype was identified by binding studies in the opossum kidney and in cell lines from this organ (OK cells).Surprisingly, the α2C-Adrenoceptor subtype seems not to play a major role in cardiovascular regulation or the other classical effects of α2-Adrenergic receptors. Some researchers have suggested that the α2C-Adrenoceptor subtype may play a role in modulating motor behaviour and perhaps in memory processes.
