PIGQ (Phosphatidylinositol Glycan Anchor Biosynthesis Class Q) is a Protein Coding gene. Diseases associated with PIGQ include Epileptic Encephalopathy, Early Infantile, 15 and Acute Contagious Conjunctivitis. Among its related pathways are Glycosylphosphatidylinositol (GPI)-anchor biosynthesis and Metabolism. PIGQ is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. PIGQ encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). Alternatively spliced transcript variants encoding different isoforms have been found for PIGQ.
