IGFBP4 (Insulin Like Growth Factor Binding Protein 4) is a Protein Coding gene. Diseases associated with IGFBP4 include Insulin-Like Growth Factor I and Renal Osteodystrophy. Among its related pathways are Wnt signaling network and Myometrial Relaxation and Contraction Pathways. IGFBP4 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
