CD300E encodes a member of the CD300 glycoprotein family of cell surface proteins expressed on myeloid cells. The protein interacts with the TYRO protein tyrosine kinase-binding protein and is thought to act as an activating receptor. CD300E (CD300e Molecule) is a Protein Coding gene. Diseases associated with CD300E include Tungiasis and Lice Infestation. Among its related pathways are Class I MHC mediated antigen processing and presentation and RET signaling. An important paralog of CD300E is CD300C.