CDC25C(cell division cycle 25C) encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It also suppresses p53-induced growth arrest. Multiple alternatively spliced transcript variants of CDC25C have been described.蛋白别名为:CDC25C; M-phase inducer phosphatase 3; Dual specificity phosphatase Cdc25C;基因ID为:995;蛋白质ID:P30307
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:human Cdc25C around the phosphorylation site of T48.