ADGRG1(adhesion G protein-coupled receptor G1) encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in ADGRG1 are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants.蛋白别名为:GPR56; TM7LN4; TM7XN1; G-protein coupled receptor 56; Protein TM7XN1;基因ID为:9289;蛋白质ID:Q9Y653
应用类型
WB,IF,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IF: 1:200-1:1000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human GPR56. at AA rangle: 220-300