URI1(URI1, prefoldin like chaperone) encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. URI1 may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for URI1, and a pseudogene of this gene is located on the long arm of chromosome 22.蛋白别名为:URI1; C19orf2; NNX3; PPP1R19; RMP; URI; Unconventional prefoldin RPB5 interactor 1; Protein NNX3; Protein phosphatase 1 regulatory subunit 19; RNA polymerase II subunit 5-mediating protein; RPB5-mediating protein;基因ID为:8725;蛋白质ID:O94763
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human RMP. at AA rangle: 390-470