BinCARD 多克隆抗体-BinCARD Polyclonal Antibody代理/参数/厂家-一抗-艾美捷科技有限公司

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背景资料: BinCARD (Bcl10-interacting CARD protein) is a 228 amino acid protein that exists as two alternatively spiced isoforms. BinCARD localizes to nucleus and is expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart, liver, thymus and brain. Containing a CARD domain, BinCARD plays a role in inhibiting the effects of Bcl10-induced activation of NFκB possibly by inhibiting the phosphorylation of Bcl10 in a CARD-dependent manner. The BinCARD gene maps to chromosome 9q22.31. Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKAP.
蛋白别名为：C9orf89; Bcl10-interacting CARD protein; BinCARD;基因ID为：84270；蛋白质ID:Q96LW7

应用类型: IHC-p，ELISA
补充：最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.

保存建议: 厂家推荐蓝冰运输.在发货后能在-20℃保存1年.为最大限度的避免损失，请在打开管盖之前融化抗体并离心.我们建议使用前分装以避免反复冻融.
本产品为液体形式,溶解于PBS缓冲液中，含50%甘油，0.5%BSA和0.02%NaN3.

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