GJC2(gap junction protein gamma 2) encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. GJC2 plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in GJC2 are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.蛋白别名为:GJC2; GJA12; Gap junction gamma-2 protein; Connexin-46.6; Cx46.6; Connexin-47; Cx47; Gap junction alpha-12 protein;基因ID为:57165;蛋白质ID:Q5T442
应用类型
WB,IF,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IF: 1:200-1:1000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the N-terminal region of human Connexin 47. at AA rangle: 40-120