ERAS encodes a constitutively active member of the small GTPase Ras protein family. The ES cell expressed Ras activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. ERAS may be involved in cancer and chemotherapy resistance.蛋白别名为:ERAS; HRAS2; HRASP; GTPase ERas; E-Ras; Embryonic stem cell-expressed Ras;基因ID为:3266;蛋白质ID:Q7Z444
应用类型
WB,IF,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IF: 1:200-1:1000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human E-Ras. at AA rangle: 160-240