BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines.Breast cancer metastasis-suppressor 1 encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.蛋白别名为:BRMS1; Breast cancer metastasis-suppressor 1;基因ID为:25855;蛋白质ID:Q9HCU9
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.