PAOX (Polyamine Oxidase (Exo-N4-Amino)) is a Protein Coding gene. Among its related pathways are Metabolism and cytochrome P450. GO annotations related to this gene include receptor binding and polyamine oxidase activity. An important paralog of this gene is KDM1B.Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.蛋白别名为：PAOX; PAO; Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; Polyamine oxidase;基因ID为：196743；蛋白质ID:Q6QHF9
应用类型
WB，IHC-p，ELISA补充：最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-300 ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽：the Internal region of human PAOX. at AA rangle: 260-340
